That day 100 percent of sales donated locally, will go to the Children's Miracle Network of Beaumont Children's Hospital - specifically the student heart check program.
The program selected is where student athletes get their heart screened so they can catch heart problems in time.
All locations of Jersey Mike's in Michigan and across the country are donating to various causes.
"Most businesses for charity don't give 100 percent of their sales," said a Children's Miracle Network representative. "One-hundred percent of everything they sell tomorrow is going to go back top supporting the Student Heart Check Program."
FOX 2's Deena Centofanti went to Jersey Mike's in Birmingham to learn about building the perfect sub and to learn more about the "Day of Giving."
Watch the video to learn more.