Sharnique Smith was last seen at 7 a.m. Feb. 13 in the 2000 block of W. Grand Blvd by her mother when she was dropped off for school.
Sharnique's mother says she has not heard from her since.
She is described as a 5 feet 6 inch black female, weighing about 170 pounds. Sharnique has a medium complexion with black hair and brown eyes.
She was last seen wearing a blue shirt and khaki pants.
According to police she is in good physical condition, but she suffers from depression.
Anyone with information should contact Detroit police at (313) 596-5300.