Tiaona Evans was last seen in the 600 block of Martin Luther King Boulevard at the Woodward Corridor Family Health Center at 2 p.m.
Police say she has some mental health issues and is on medication for those disorders. She was last seen leaving the medical clinic on foot and has not been seen since.
She is described as black, 5 feet 3 inches and 150 pounds. She has a medium complexion with black shoulder length hair.
She was last seen wearing a red shirt, black leggings and black gym shoes.